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1

Stereocontrolled Total Synthesis of Bengazole A: A Marine Bisoxazole Natural Product Displaying Potent Antifungal Properties

James A. Bull, Emily P. Balskus, Richard A. J. Horan, Martin Langner, Steven V. Ley

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

2

Metabolic functions of the human gut microbiota: the role of metalloenzymes

Rajakovich, Lauren J., Balskus, Emily P.

Journal:

Natural Product Reports

Year:

2019

Language:

english

File:

PDF, 5.24 MB

english, 2019

3

Investigating the Initial Steps in the Biosynthesis of Cyanobacterial Sunscreen Scytonemin

Balskus, Emily P., Walsh, Christopher T.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 120 KB

english, 2008

4

Engineering chemical interactions in microbial communities

Kenny, Douglas J., Balskus, Emily P.

Journal:

Chemical Society Reviews

Year:

2018

Language:

english

File:

PDF, 4.71 MB

english, 2018

5

A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia

Peck, Spencer C., Denger, Karin, Burrichter, Anna, Irwin, Stephania M., Balskus, Emily P., Schleheck, David

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

File:

PDF, 1.13 MB

2019

6

Interfacing Microbial Styrene Production with a Biocompatible Cyclopropanation Reaction

Wallace, Stephen, Balskus, Emily P.

Journal:

Angewandte Chemie International Edition

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

7

Using non-enzymatic chemistry to influence microbial metabolism

Wallace, Stephen, Schultz, Erica E, Balskus, Emily P

Journal:

Current Opinion in Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

8

Opportunities for merging chemical and biological synthesis

Wallace, Stephen, Balskus, Emily P

Journal:

Current Opinion in Biotechnology

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

9

Enzymes that detoxify marine toxins

McCallum, Monica E., Balskus, Emily P.

Journal:

Year:

2019

File:

PDF, 186 KB

2019

10

Cholesterol Metabolism by Uncultured Human Gut Bacteria Influences Host Cholesterol Level

Kenny, Douglas J., Plichta, Damian R., Shungin, Dmitry, Koppel, Nitzan, Hall, A. Brantley, Fu, Beverly, Vasan, Ramachandran S., Shaw, Stanley Y., Vlamakis, Hera, Balskus, Emily P., Xavier, Ramnik J.

Journal:

Cell Host & Microbe

Year:

2020

File:

PDF, 3.65 MB

2020

11

Discovery of a Diazo-Forming Enzyme in Cremeomycin Biosynthesis

Waldman, Abraham J., Balskus, Emily P.

Journal:

Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 869 KB

english, 2018

12

Enzymes that detoxify marine toxins

McCallum, Monica E., Balskus, Emily P.

Journal:

Year:

2019

Language:

english

File:

PDF, 186 KB

english, 2019

13

Total Synthesis of Potent Antifungal Marine Bisoxazole Natural Products Bengazoles A and B

James A. Bull, Emily P. Balskus, Richard A. J. Horan, Martin Langner, Steven V. Ley

Journal:

Chemistry - A European Journal

Year:

2007

Language:

english

File:

PDF, 479 KB

english, 2007

14

The Human Microbiome

Balskus, Emily P.

Journal:

ACS Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 233 KB

english, 2018

15

An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin

Ng, Tai L., Rohac, Roman, Mitchell, Andrew J., Boal, Amie K., Balskus, Emily P.

Journal:

Year:

2019

File:

PDF, 9.86 MB

2019

16

An Enzymatic Cyclopentyl[ b ]indole Formation Involved in Scytonemin Biosynthesis

Balskus, Emily P., Walsh, Christopher T.

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 610 KB

english, 2009

17

Designer Micelles Accelerate Flux Through Engineered Metabolism in E. coli and Support Biocompatible Chemistry

Wallace, Stephen, Balskus, Emily P.

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 2.51 MB

english, 2016

18

Rescuing Auxotrophic Microorganisms with Nonenzymatic Chemistry

Lee, Yunmi, Umeano, Afoma, Balskus, Emily P.

Journal:

Angewandte Chemie

Year:

2013

Language:

english

File:

PDF, 964 KB

english, 2013

19

The biosynthesis of cyanobacterial sunscreen scytonemin in intertidal microbial mat communities

Emily P. Balskus, Rebecca J. Case, Christopher T. Walsh

Journal:

FEMS Microbiology Ecology

Year:

2011

Language:

english

File:

PDF, 953 KB

english, 2011

20

Colibactin: understanding an elusive gut bacterial genotoxin

Balskus, Emily P.

Journal:

Natural Product Reports

Year:

2015

Language:

english

File:

PDF, 916 KB

english, 2015

21

Biosynthesis-Assisted Structural Elucidation of the Bartolosides, Chlorinated Aromatic Glycolipids from Cyanobacteria

Leão, Pedro N., Nakamura, Hitomi, Costa, Margarida, Pereira, Alban R., Martins, Rosário, Vasconcelos, Vitor, Gerwick, William H., Balskus, Emily P.

Journal:

Angewandte Chemie International Edition

Year:

2015

Language:

english

File:

PDF, 3.50 MB

english, 2015

22

Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins

Koppel, Nitzan, Bisanz, Jordan E, Pandelia, Maria-Eirini, Turnbaugh, Peter J, Balskus, Emily P

Journal:

Year:

2018

Language:

english

File:

PDF, 3.85 MB

english, 2018

23

A Sequential Tetra-n-propylammonium Perruthenate (TPAP)—Wittig Oxidation Olefination Protocol.

Rachel N. MacCoss, Emily P. Balskus, Steven V. Ley

Journal:

Year:

2004

File:

PDF, 169 KB

2004

24

Natural products: Sponge symbionts play defense

Balskus, Emily P

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 287 KB

english, 2014

25

Biosynthesis-Assisted Structural Elucidation of the Bartolosides, Chlorinated Aromatic Glycolipids from Cyanobacteria

Leão, Pedro N., Nakamura, Hitomi, Costa, Margarida, Pereira, Alban R., Martins, Rosário, Vasconcelos, Vitor, Gerwick, William H., Balskus, Emily P.

Journal:

Angewandte Chemie

Year:

2015

Language:

english

File:

PDF, 3.48 MB

english, 2015

26

Anaerobic 4-hydroxyproline utilization: discovery of a new glycyl radical enzyme in the human gut microbiome uncovers a widespread microbial metabolic activity

Huang, Yolanda Y., Martínez-del Campo, Ana, Balskus, Emily P.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

27

Discovery of small molecule protease inhibitors by investigating a widespread human gut bacterial biosynthetic pathway

Schneider, Benjamin A., Balskus, Emily P.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.27 MB

english, 2018

28

Spin-transition behaviour in chains of FeII bridged by 4-substituted 1,2,4-triazoles carrying alkyl tails

Roubeau, Olivier, Alcazar Gomez, Jose´ M., Balskus, Emily, Kolnaar, Jeroen J. A., Haasnoot, Jaap G., Reedijk, Jan

Journal:

New Journal of Chemistry

Year:

2001

Language:

english

File:

PDF, 177 KB

english, 2001

29

Structural Analysis of Spiro β-Lactone Proteasome Inhibitors

Groll, Michael, Balskus, Emily P., Jacobsen, Eric N.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 734 KB

english, 2008

30

Total Synthesis of (−)-Hennoxazole A

Smith, Thomas E., Kuo, Wen-Hsin, Balskus, Emily P., Bock, Victoria D., Roizen, Jennifer L., Theberge, Ashleigh B., Carroll, Kathleen A., Kurihara, Tomoki, Wessler, Jeffrey D.

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 271 KB

english, 2008

31

Addressing Infectious Disease Challenges by Investigating Microbiomes

Balskus, Emily P.

Journal:

ACS Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 143 KB

english, 2016

32

The Cremeomycin Biosynthetic Gene Cluster Encodes a Pathway for Diazo Formation

Waldman, Abraham J., Pechersky, Yakov, Wang, Peng, Wang, Jennifer X., Balskus, Emily P.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

33

Heteroatom–Heteroatom Bond Formation in Natural Product Biosynthesis

Waldman, Abraham J., Ng, Tai L., Wang, Peng, Balskus, Emily P.

Journal:

Chemical Reviews

Year:

2017

Language:

english

File:

PDF, 15.78 MB

english, 2017

34

Synthetic Studies Toward Hennoxazole A. Use of a Selective Bisoxazole Alkylation as the Key Fragment Coupling.

Thomas E. Smith, Emily P. Balskus

Journal:

Year:

2002

File:

PDF, 30 KB

2002

35

The reactivity of an unusual amidase may explain colibactin’s DNA cross-linking activity

Jiang, Yindi, Stornetta, Alessia, Villalta, Peter W., Wilson, Matthew R., Boudreau, Paul D., Zha, Li, Balbo, Silvia, Balskus, Emily P.

Journal:

Journal of the American Chemical Society

Year:

2019

Language:

english

File:

PDF, 1.46 MB

english, 2019

36

Discovery of C C bond-forming and bond-breaking radical enzymes: enabling transformations for metabolic engineering

Fu, Beverly, Balskus, Emily P

Journal:

Current Opinion in Biotechnology

Year:

2020

File:

PDF, 1.28 MB

2020

37

Gut bacterial phospholipase Ds support disease-associated metabolism by generating choline

Chittim, Carina L., Martínez del Campo, Ana, Balskus, Emily P.

Journal:

Nature Microbiology

Year:

2018

Language:

english

File:

PDF, 1.84 MB

english, 2018

38

The mysteries of macrocyclic colibactins

Carlson, Erik S., Balskus, Emily P.

Journal:

Nature Chemistry

Year:

2019

Language:

english

File:

PDF, 769 KB

english, 2019

39

Metabolic, Epigenetic, and Transgenerational Effects of Gut Bacterial Choline Consumption

Romano, Kymberleigh A., Martinez-del Campo, Ana, Kasahara, Kazuyuki, Chittim, Carina L., Vivas, Eugenio I., Amador-Noguez, Daniel, Balskus, Emily P., Rey, Federico E.

Journal:

Cell Host & Microbe

Year:

2017

Language:

english

File:

PDF, 1.90 MB

english, 2017

40

Chemical signaling at the eukaryotic/prokaryotic interface

Dorrestein, Pieter C., Balskus, Emily P.

Journal:

Chemical Society Reviews

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

41

A peroxodiiron(III) intermediate mediating both N -hydroxylation steps in biosynthesis of the N -nitrosourea pharmacophore of streptozotocin by SznF

McBride, Molly, Sil, Debangsu, Ng, Tai L., Crooke, Anne Marie, Kenney, Grace E., Tysoe, Christina R., Zhang, Bo, Balskus, Emily P., Boal, Amie K., Krebs, Carsten, Bollinger, J. Martin

Journal:

Journal of the American Chemical Society

Year:

2020

File:

PDF, 1.16 MB

2020

42

Total Synthesis of (−)-Hennoxazole A

Smith, Thomas E., Kuo, Wen-Hsin, Bock, Victoria D., Roizen, Jennifer L., Balskus, Emily P., Theberge, Ashleigh B.

Journal:

Organic Letters

Year:

2007

Language:

english

File:

PDF, 80 KB

english, 2007

43

Berichtigung: Biosynthesis-Assisted Structural Elucidation of the Bartolosides, Chlorinated Aromatic Glycolipids from Cyanobacteria

Leão, Pedro N., Nakamura, Hitomi, Costa, Margarida, Pereira, Alban R., Martins, Rosário, Vasconcelos, Vitor, Gerwick, William H., Balskus, Emily P.

Journal:

Angewandte Chemie

Year:

2016

Language:

german

File:

PDF, 354 KB

german, 2016

44

Stereocontrolled Total Synthesis of Bengazole A: A Marine Bisoxazole Natural Product Displaying Potent Antifungal Properties

James A. Bull, Emily P. Balskus, Richard A. J. Horan, Martin Langner, Steven V. Ley

Journal:

Angewandte Chemie

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

45

A Biocompatible Alkene Hydrogenation Merges Organic Synthesis with Microbial Metabolism

Sirasani, Gopal, Tong, Liuchuan, Balskus, Emily P.

Journal:

Angewandte Chemie International Edition

Year:

2014

Language:

english

File:

PDF, 1023 KB

english, 2014

46

Using Chemical Knowledge to Uncover New Biological Function: Discovery of the Cylindrocyclophane Biosynthetic Pathway

Nakamura, Hitomi, Balskus, Emily

Journal:

Year:

2013

Language:

english

File:

PDF, 585 KB

english, 2013

47

Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring

Zha, Li, Jiang, Yindi, Henke, Matthew T, Wilson, Matthew R, Wang, Jennifer X, Kelleher, Neil L, Balskus, Emily P

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 458 KB

english, 2017

48

Gut Microbiota: Rational Manipulation of Gut Bacterial Metalloenzymes Provides Insights into Dysbiosis and Inflammation

M. Rekdal, Vayu, Balskus, Emily P.

Journal:

Year:

2018

Language:

english

File:

PDF, 608 KB

english, 2018

49

Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin

Zha, Li, Wilson, Matthew R., Brotherton, Carolyn A., Balskus, Emily P

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 1.88 MB

english, 2016

50

Announcement of 2019 Keystone Symposia Conference: “Microbiome: Chemical Mechanisms and Biological Consequences”

Balskus, Emily P., Turnbaugh, Peter J., Wolan, Dennis W.

Journal:

Year:

2018

Language:

english

File:

PDF, 163 KB

english, 2018

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